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By an overwhelming majority, the U.S. House of Representatives has voted to repeal U.S. President Barack Obama’s socialized medicine law – a party-line vote that marks the opening salvo in a protracted war against this costly, job-killing big government abomination.

All 242 GOP lawmakers voted in favor of repeal – while only three Democrats (Dan Boren of Oklahoma, Mike McIntyre of North Carolina and Mike Ross of Arkansas) broke ranks and joined them.

Among South Carolina lawmakers, U.S. Reps. Jeff Duncan, Trey Gowdy, Mick Mulvaney, Tim Scott and Joe Wilson (all Republicans) voted in favor of repeal. U.S. Rep. Jim Clyburn, the lone Democrat in the S.C. delegation, voted “nay.”

Last March, “Obamacare” passed the U.S. House by a narrow 219-212 vote – with 178 Republicans and 34 Democrats voting against the bill.

After Obama signed the bill into law, Democrats vowed to undertake a massive educational and public relations campaign aimed at selling the American public on the benefits of the legislation. They didn’t … and health care data that’s been released over the past year hasn’t helped their cause (click here, here, here and here for a few examples of that).

Not surprisingly, Obamacare was one of the main reasons the Democratic party was thumped at the polls in November – giving up its majority in the U.S. House and surrendering six seats in the U.S. Senate.

In recent weeks, Republicans advanced repeal based almost exclusively on economic arguments.

In a letter to lawmakers prior to the vote, a group of 200 economists described Obamacare as “a threat to U.S. businesses,” one that “will place a crushing debt burden on future generations of Americans.” Meanwhile, a new report issued by The Cato Institute found that Obamacare will result in massive new Medicaid expenses for cash-strapped states.

The Obamacare repeal bill now heads to the U.S. Senate, where Democratic leaders have vowed to block it. Even if by some miracle it were to clear the Senate, though, it faces a certain presidential veto.

That means Republicans will use other tools to chip away at the law – including blocking the promulgation of its various regulations and refusing to appropriate money toward its implementation.

All of this means that Obamacare will continue to loom large in the upcoming 2012 election -which in addition to the battle for the presidency will include numerous competitive Senate contests.

“We will not stop until we put a president in the White House who will repeal this,” said U.S. Rep Michele Bachmann, one of the Republicans who may challenge Obama.

Finally, a total of 27 states are currently suing the federal government in an effort to block various provisions of Obamacare – including its unconstitutional individual mandates.

“Obamacare” Repeal (Official Roll Call)